The Bills defeated the Rams 31–10 in the 2022 NFL season-opener.

Image:Twitter-NFL

Josh Allen dominated the Rams, playing aggressively.

Image:Twitter-NFL

Josh Allen accounts for four touchdowns in 297 yards when playing the game.

Image:Twitter-NFL

Josh Allen scored 26 runs out of a total score of 31.

Image:Twitter-NFL

Allen ran 56 yards for play 13:27 for a 4-yard TD.

Image:Twitter-NFL

After being tied at score 10 at halftime, the Bills went on a 21-0 lead to the Rams in the second half.

Image:Twitter-NFL

Score of Bills :  Q1 - 7;  Q2 - 3;  Q3 - 7;  Q4 - 14; F = 31

Image:Twitter-NFL

Score of Rams :  Q1 - 0;  Q2 - 10;  Q3 - 0;  Q4 - 0; F = 10

Image:Twitter-NFL